Nos Publications

Factors Associated with the 18-Month Cumulative Incidence of Seroconversion of Active Infection with Taenia solium Cysticercosis: A Cohort Study among Residents of 60 Villages in Burkina Faso

Veronique Dermauw,1* H ´ el ` ene Carabin,2 Rasman ´ e Ganaba,3 Assana Ciss ´ e,4 Z ´ ekiba Tarnagda,4 Sarah Gabri ¨ el,5 Pierre Dorny,1,6 and Athanase Millogo7 1Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium; 2Department of Biostatistics and Epidemiology, College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma; 3Agence de Formation de Recherche et d’Expertise en Sant ´ e pour l’Afrique (AFRICSant ´ e), Bobo Dioulasso, Burkina Faso; 4Institut de Recherche en Sciences de la Sant ´ e, Bobo Dioulasso, Burkina Faso; 5Department of Veterinary Public Health and Food Safety, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium; 6Laboratory of Veterinary Parasitology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium; 7Centre Hospitalier Universitaire Souro Sanou, Bobo Dioulasso, Burkina Faso Abstract Taeniasis/cysticercosis (CC) is an important disease complex with significant burden. This large-scale cohort study aimed at estimating and exploring individual- and village-level factors associated with the cumulative incidences of seroconversion (SC) and seroreversion (SR) of active human CC in three provinces of Burkina Faso. In 60 villages, blood samples were collected and interviews regarding sociodemographic variables and knowledge, attitude, and practices toward the disease complex were conducted at baseline and 18-month follow-up (N = 2,211), with the presence of active CC being determined using the B158/B60 antigen enzyme-linked immunosorbent assay (Ag-ELISA). The 18-month Ag SC and SR were estimated at 3.3% (95% confidence interval [CI]: 2.6; 4.2%) and 35.8% (95% CI: 24.5; 48.5%), respectively. Marked provincial differences were found for the 18-month Ag SC (Boulkiemde: cumulative incidence ratio [CIR]: 2.41 (95% CI: 1.21; 4.78) and Nayala: CIR: 3.28 (95% CI: 1.37; 7.84), compared withSanguie), while not being significantly associated with other sociodemographic factors. A continued refraining from pork consumption was associated with a lower 18-month Ag SC (CIR: 0.55 [95% CI: 0.28; 1.07]), whereas at the village level, the percentage of households owning pigs was associated with a higher 18-month Ag SC (CIR: 1.03 [95% CI: 1.01; 1.05]). In conclusion, this is one of few cohort studies and the first to have enough power to assess possible causal links between individual- and village-level variables and CC in humans. Variables linked to province, pig raising, and pork consumption behaviors were found to cause Ag SC in humans. The latter results further support the importance of adopting a One Health approach to the control of CC (suite…)

Par afriAdmin, il y a
Nos Publications

Involving male partners in maternity care in Burkina Faso: a randomized controlled trial

Marina AS Daniele,a Rasmané Ganaba,b Sophie Sarrassat,a Simon Cousens,a Clémentine Rossier,c Seydou Drabo,d Djeneba Ouedraogob & Veronique Filippia Objective         To determine whether an intervention to involve the male partners of pregnant women in maternity care inuenced care-seeking, healthy breastfeeding and contraceptive practices after childbirth in urban Burkina Faso. Methods        In a non-blinded, multicentre, parallel-group, superiority trial, 1144 women were assigned by simple randomization to two  study arms: 583 entered the intervention arm and 561 entered the control arm. All women were cohabiting with a male partner and had a low-risk pregnancy. Recruitment took place at 20 to 36 weeks’ gestation at fve primary health centres in Bobo-Dioulasso. The intervention comprised three educational sessions: (i) an interactive group session during pregnancy with male partners only, to discuss their role; (ii) a counselling session during pregnancy for individual couples; and (iii) a postnatal couple counselling session. The control group received routine care only. We followed up participants at 3 and 8 months postpartum. Findings        The follow-up rate was over 96% at both times. In the intervention arm, 74% (432/583) of couples or men attended at least two study sessions. Attendance at two or more outpatient postnatal care consultations was more frequent in the intervention than the control group (risk dierence, RD: 11.7%; 95% confdence interval, CI: 6.0 to 17.5), as was exclusive breastfeeding 3 months postpartum (RD: 11.4%; 95% CI: 5.8 to 17.2) and eective modern contraception use 8 months postpartum (RD: 6.4%; 95% CI: 0.5 to 12.3). Conclusion Involving men as supportive partners in maternity care was associated with better adherence to recommended healthy practices after childbirth. (suite…)

Par afriAdmin, il y a
Nos Publications

Development of a health education intervention strategy using an implementation research method to control taeniasis and cysticercosis in Burkina Faso

Helena Ngowi1*, Ivan Ozbolt2,3, Athanase Millogo4, Veronique Dermauw5, Télesphore Somé6, Paul Spicer7, Lori L. Jervis7, Rasmané Ganaba6, Sarah Gabriel5, Pierre Dorny5 and Hélène Carabin8 Abstract Background: Taeniasis and cysticercosis are two diseases caused by Taenia solium, a parasite transmitted between humans and pigs, leading to considerable economic loss and disabilities. Transmission of the parasite is linked to environmental and behavioural factors such as inadequate sanitation and hygiene, poor pig management, and consumption of infected pork. This study used implementation research method to design a health education intervention strategy for reducing T. solium infections in Burkina Faso, a country endemic for the parasite. Methods: Eighteen group discussions were conducted with 818 participants each in three villages. In addition, structured interviews were conducted among 4 777 participants and 2 244 pig owners, who were selected through cluster random sampling in 60 villages of three provinces of Burkina Faso. Both approaches assessed knowledge and practices related to T. solium. The information obtained was used to develop a community-adapted health education intervention strategy to control taeniasis and cysticercosis in Burkina Faso. (suite…)

Par afriAdmin, il y a